VACCINE STABILITY (brief) - Australian Immunisation Handbook, 8th Edition page 38   Full table

The following vaccines are unstable at room temperature:

  • BCG (Bacille Calmette-Guérin) vaccine

  • Measles-mumps-rubella (MMR) vaccine

  • Oral poliomyelitis vaccine (OPV)

  • Varicella-zoster vaccine

  • Yellow fever vaccine

  • All reconstituted vaccines

The following vaccines must not be exposed to light:

  • BCG (Bacille Calmette-Guérin) vaccine

  • Reconstituted measles-mumps-rubella (MMR) vaccine

  • Monovalent rubella vaccine

  • Oral poliomyelitis vaccine (OPV)

  • Varicella-zoster vaccine (VZV)

  • Most DTPa-containing vaccines

  • Meningococcal C conjugate vaccine

  • Yellow fever vaccine.


Do not freeze the following vaccines:

  • Diphtheria-tetanus-pertussis containing vaccines

  • Haemophilus influenzae type b (the exception being the lyophilised PRP-T vaccines)

  • Hepatitis B-containing vaccines

  • Hepatitis A-containing vaccines

  • Influenza vaccine

  • Pneumococcal (polysaccharide and conjugate) vaccines

  • Meningococcal C conjugate vaccines

  • Japanese encephalitis vaccine

  • All reconstituted vaccines

  • All combinations of these vaccines

  • Vaccine diluents

Note: Several other less frequently used vaccines (eg. rabies and typhoid) are also damaged by freezing.

If the vaccines listed above have been exposed to temperatures 0°C and below, do not use.